Description

1-Oxa-6-Azaspiro[3.5]Nonane-6-Carboxylic Acid, 2,2,3,3,7,7-Hexamethyl-, Ethyl Ester is a high-value, multifunctional spirocyclic building block designed for advanced organic synthesis. This compound is prized for its rigid, three-dimensional structure which is instrumental in modulating the physicochemical properties of target molecules, particularly in pharmaceutical research. It serves as a critical intermediate for medicinal chemists and process development scientists working in drug discovery, agrochemical development, and materials science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its spirocyclic core can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Materials Science Research: Employed in the development of specialty polymers and advanced organic frameworks with unique thermal or mechanical properties.
• Chemical Biology Probes: Utilized as a scaffold for designing molecular probes to study enzyme function and protein-protein interactions.

Basic Information

Product Name	1-Oxa-6-Azaspiro[3.5]Nonane-6-Carboxylic Acid, 2,2,3,3,7,7-Hexamethyl-, Ethyl Ester
CAS No.	240113-59-1
Molecular Formula	C14H25NO3
Molecular Weight	255.35 g/mol
Synonyms	Ethyl 2,2,3,3,7,7-hexamethyl-1-oxa-6-azaspiro[3.5]nonane-6-carboxylate; 6-Carbethoxy-2,2,3,3,7,7-hexamethyl-1-oxa-6-azaspiro[3.5]nonane; Hexamethyl-1-oxa-6-azaspiro[3.5]nonane-6-carboxylic acid ethyl ester; 1-Oxa-6-azaspiro[3.5]nonane-6-carboxylic acid, 2,2,3,3,7,7-hexamethyl-, ethyl ester; Spirocyclic β-amino acid ester derivative.
EINECS	Contact for details

Quality Control

Our 1-Oxa-6-Azaspiro[3.5]Nonane-6-Carboxylic Acid, 2,2,3,3,7,7-Hexamethyl-, Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.