Description

5-Bromo-4-Chloro-4,5,5-Trifluoropentanoic Acid is a high-value fluorinated organic building block characterized by its unique halogenated and trifluoromethylated pentanoic acid structure. This compound is essential for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its specific halogen and fluorine substitution pattern enables precise molecular modifications. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Fluorinated Polymer Modification: Employed to introduce halogen and carboxylic acid functionalities into polymer chains, altering surface properties and reactivity.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions and as a precursor for more complex fluorinated molecules in academic and industrial research laboratories.
• Protease Inhibitor Development: The carboxylic acid and halogen groups make it a potential scaffold for designing enzyme inhibitors in medicinal chemistry programs.

Basic Information

Product Name	5-Bromo-4-Chloro-4,5,5-Trifluoropentanoic Acid
CAS No.	232602-79-8
Molecular Formula	C5H5BrClF3O2
Molecular Weight	268.44 g/mol
Synonyms	4,5,5-Trifluoro-5-bromo-4-chloropentanoic Acid; Pentanoic acid, 5-bromo-4-chloro-4,5,5-trifluoro-; 5-Bromo-4-chloro-4,5,5-trifluorovaleric Acid; 232602-79-8; 4-Chloro-5-bromo-4,5,5-trifluoropentanoic Acid; 4,5,5-Trifluoro-4-chloro-5-bromopentanoic Acid; 5-Bromo-4-chloro-4,5,5-trifluoro-pentanoic acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Chloro-4,5,5-Trifluoropentanoic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and production use. We employ advanced analytical techniques including HPLC, GC, NMR, and MS for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. Our quality system supports compliance with cGMP and ISO standards for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere or inert gas to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.