Description

2-Butynoic Acid, 4-[(Methoxycarbonyl)Amino]-, Methyl Ester is a specialized alkyne-containing building block with a carbamate-protected amino group. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex molecules, particularly in pharmaceutical research and fine chemical production. It is primarily utilized by R&D chemists and process development scientists in the life sciences and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of active pharmaceutical ingredients (APIs), especially those requiring alkyne functionality for click chemistry or further derivatization.
• Agrochemical Synthesis: Used in the research and development of novel crop protection agents and herbicides, leveraging its reactive alkyne and protected amine groups.
• Peptidomimetics & Bioconjugation: Serves as a building block for creating peptide analogs and for linking molecules to biomolecules via its alkyne handle.
• Material Science Research: Employed in the synthesis of specialty polymers and functional materials where its specific molecular architecture can impart desired properties.
• Chemical Biology Probes: Acts as a precursor for developing probes and tags used to study biological processes and interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific molecular scaffold.

Basic Information

Item	Detail
Product Name	2-Butynoic Acid, 4-[(Methoxycarbonyl)Amino]-, Methyl Ester
CAS No.	230286-83-6
Molecular Formula	C8H9NO4
Molecular Weight	183.16 g/mol
Synonyms	Methyl 4-[(methoxycarbonyl)amino]-2-butynoate; 4-(Methoxycarbonylamino)but-2-ynoic acid methyl ester; Methyl 4-(N-methoxycarbonylamino)but-2-ynoate; 2-Butynoic acid, 4-[(methoxycarbonyl)amino]-, methyl ester; 4-Carbamoyloxy-2-butynoic acid methyl ester (related); N-Methoxycarbonyl propargylglycine methyl ester
EINECS	Contact for details

Quality Control

Every batch of 2-Butynoic Acid, 4-[(Methoxycarbonyl)Amino]-, Methyl Ester is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.