Description

(1S-4R)-4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]- 2-Cyclopentene-1-Carboxylic Acid Methyl Ester is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex, biologically active molecules, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical manufacturers in the development of new therapeutic agents, particularly in antiviral and oncology drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially for nucleoside analogs and protease inhibitors.
• Antiviral Drug Research: Serves as a critical precursor in the development of novel antiviral medications targeting specific viral enzymes.
• Oncology Therapeutics: Used in the research and production of targeted cancer therapies that require specific stereochemistry for efficacy.
• Asymmetric Synthesis: Employed in organic chemistry for constructing complex molecular architectures with high enantiomeric purity.
• Process Chemistry & Scale-Up: Supports route scouting and optimization from laboratory to pilot and commercial manufacturing scales.
• Contract Development and Manufacturing Organizations (CDMOs): Supplied to CDMOs for custom synthesis projects under cGMP guidelines.

Basic Information

Product Name	(1S-4R)-4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]- 2-Cyclopentene-1-Carboxylic Acid Methyl Ester
CAS No.	229613-93-8
Molecular Formula	C13H21NO4
Molecular Weight	255.31 g/mol
Synonyms	(1S,4R)-4-[(tert-Butoxycarbonyl)amino]-2-cyclopentene-1-carboxylic acid methyl ester; (1S,4R)-Methyl 4-((tert-butoxycarbonyl)amino)-2-cyclopentene-1-carboxylate; (1S,4R)-Boc-Amino-2-cyclopentene-1-carboxylic acid methyl ester; (1S,4R)-4-(Boc-amino)-2-cyclopentene-1-carboxylic acid methyl ester; (1S,4R)-4-(tert-Butoxycarbonylamino)cyclopent-2-ene-1-carboxylic acid methyl ester; Boc-Cyclopentenyl-Glycine Methyl Ester (stereospecific); 229613-93-8; Contact for EINECS details.

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols suitable for pharmaceutical development. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles. We operate under a quality management system and can supply material suitable for use under cGMP conditions for non-clinical and clinical stage manufacturing, upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.