Description

.Beta.-D-Galactopyranose, 1,6-Anhydro-2-o-(1,1-Dimethylethyl)Dimethylsilyl-, 4-Acetate is a high-purity, protected carbohydrate derivative, specifically a silylated and acetylated anhydro-galactose, serving as a critical chiral building block and synthetic intermediate. Its value lies in providing a chemically defined scaffold for the controlled synthesis of complex oligosaccharides, glycoconjugates, and other bioactive molecules. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly in carbohydrate-based drug discovery, and for the production of specialized reagents in glycochemistry and biochemical research.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel glycosidase inhibitors, antiviral agents, and other carbohydrate-based therapeutics.
• Glycochemistry Research: Serves as a protected galactose donor or acceptor in the stepwise construction of complex oligosaccharides and glycans.
• Bioconjugate Development: Used to introduce galactose moieties onto proteins, peptides, or other carriers for targeted drug delivery or diagnostic applications.
• Chemical Biology Probes: Acts as a precursor for labeled sugar analogs used to study glycosylation pathways and carbohydrate-protein interactions.
• Process Development: Employed in route scouting and optimization for the scalable production of advanced pharmaceutical ingredients (APIs) with carbohydrate motifs.
• Academic & Industrial R&D: A valuable tool for synthetic organic chemists exploring new methodologies in stereoselective glycosylation and protecting group strategies.

Basic Information

Product Name	.Beta.-D-Galactopyranose, 1,6-Anhydro-2-o-(1,1-Dimethylethyl)Dimethylsilyl-, 4-Acetate
CAS No.	228115-74-0
Molecular Formula	C15H28O6Si
Molecular Weight	332.47 g/mol
Synonyms	1,6-Anhydro-2-O-(tert-butyldimethylsilyl)-β-D-galactopyranose 4-acetate; 2-O-(tert-Butyldimethylsilyl)-1,6-anhydro-β-D-galactopyranose 4-acetate; 1,6-Anhydro-2-O-TBDMS-β-D-galactopyranose 4-acetate; TBDMS-protected 1,6-anhydro-galactose 4-acetate; 2-O-TBDMS-1,6-anhydro-β-D-galactopyranose 4-O-acetate; 1,6-Anhydro-4-O-acetyl-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-D-galactopyranose; Protected Levogalactosan derivative
EINECS	Contact for details

Quality Control

Every batch of .Beta.-D-Galactopyranose, 1,6-Anhydro-2-o-(1,1-Dimethylethyl)Dimethylsilyl-, 4-Acetate is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) detailing key parameters such as assay, chiral purity, and impurity profiles. Our quality commitment supports applications requiring research-grade to GMP-starting material standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.