Description

(1R,3S)-1,3-Cyclohexanedicarboxylic Acid 1-Ethylester is a high-purity chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry makes it a critical precursor for the development of pharmaceuticals, agrochemicals, and specialty materials where precise molecular geometry is required. This compound is essential for researchers and manufacturers in fine chemical, pharmaceutical R&D, and advanced material science sectors seeking to create enantiomerically pure products.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer and Material Science: A monomer for creating specialized polyesters and polyamides with unique thermal and mechanical properties.
• Fine Chemical Production: Employed in the multi-step synthesis of complex natural products, flavors, and fragrances.
• Academic and Industrial Research: A valuable tool for methodological development in organic chemistry and process chemistry optimization.

Basic Information

Product Name	(1R,3S)-1,3-Cyclohexanedicarboxylic Acid 1-Ethylester
CAS No.	227783-08-6
Molecular Formula	C10H16O4
Molecular Weight	200.23 g/mol
Synonyms	(1R,3S)-1,3-Cyclohexanedicarboxylic Acid Monoethyl Ester; (1R,3S)-1-Ethoxycarbonyl-3-cyclohexanecarboxylic Acid; (1R,3S)-3-Carboxycyclohexanecarboxylic Acid Ethyl Ester; Ethyl (1R,3S)-1,3-Cyclohexanedicarboxylate; trans-1,3-Cyclohexanedicarboxylic Acid Monoethyl Ester; 1-Carboxy-3-ethoxycarbonylcyclohexane; (1R,3S)-Monoethyl Cyclohexane-1,3-dicarboxylate
EINECS	Contact for details

Quality Control

Our (1R,3S)-1,3-Cyclohexanedicarboxylic Acid 1-Ethylester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.