Description

(1R,3S)-1,3-Cyclohexanedicarboxylic Acid, Monomethyl Ester is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound is valued for its defined stereochemistry, which is critical for producing enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the research and production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemical configurations.
• Academic and Industrial R&D: A valuable reagent for methodological development in organic chemistry and process chemistry optimization.
• Polymer Chemistry: Potential monomer for creating novel polyesters and polyamides with specific structural properties.

Basic Information

Product Name	(1R,3S)-1,3-Cyclohexanedicarboxylic Acid, Monomethyl Ester
CAS No.	227783-07-5
Molecular Formula	C9H14O4
Molecular Weight	186.21 g/mol
Synonyms	(1R,3S)-1,3-Cyclohexanedicarboxylic Acid Methyl Ester; (1R,3S)-Methyl 1,3-Cyclohexanedicarboxylate; (1R,3S)-1,3-CHDA Monomethyl Ester; (1R,3S)-Cyclohexane-1,3-dicarboxylic Acid Monomethyl Ester; cis-1,3-Cyclohexanedicarboxylic Acid Monomethyl Ester (stereospecific); (1R,3S)-Hexahydroisophthalic Acid Monomethyl Ester; Methyl (1R,3S)-1,3-Cyclohexanedicarboxylate
EINECS	Contact for details

Quality Control

Our (1R,3S)-1,3-Cyclohexanedicarboxylic Acid, Monomethyl Ester is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric excess (ee) and chemical purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with full specification data are provided with each shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed after opening to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.