Description

Methyl (2S)-1-Cbz-1,2,3,4-Tetrahydro-2-Pyridinecarboxylate is a high-purity, chiral piperidine derivative, serving as a critical protected amino acid building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules, ensuring precise molecular architecture. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly those targeting the central nervous system.
• Peptidomimetics Research: Used to incorporate constrained, non-natural amino acid motifs into peptide backbones to enhance stability and bioavailability.
• Asymmetric Synthesis: Employed as a starting material or intermediate in catalytic asymmetric reactions to introduce stereogenic centers.
• Medicinal Chemistry: Utilized for structure-activity relationship (SAR) studies and the development of novel therapeutic agents.
• Agrochemical Synthesis: Acts as a building block for creating chiral active ingredients in crop protection products.
• Chemical Biology Probes: Incorporated into molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	Methyl (2S)-1-Cbz-1,2,3,4-Tetrahydro-2-Pyridinecarboxylate
CAS No.	227758-97-6
Molecular Formula	C15H19NO4
Molecular Weight	277.32 g/mol
Synonyms	(2S)-1-[(Benzyloxy)carbonyl]-1,2,3,4-tetrahydro-2-pyridinecarboxylic acid methyl ester; Methyl (2S)-1-[(benzyloxy)carbonyl]-1,2,3,4-tetrahydro-2-pyridinecarboxylate; (S)-Methyl 1-Cbz-1,2,3,4-tetrahydro-2-pyridinecarboxylate; (S)-Methyl 1-((benzyloxy)carbonyl)-1,2,3,4-tetrahydro-2-pyridinecarboxylate; 1-Cbz-2(S)-Carbomethoxypiperidine; (S)-1-Cbz-2-Piperidinecarboxylic Acid Methyl Ester; Methyl (S)-1-Cbz-piperidine-2-carboxylate; (S)-1-(Benzyloxycarbonyl)piperidine-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl (2S)-1-Cbz-1,2,3,4-Tetrahydro-2-Pyridinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-grade research and development standards. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.