Description

(2R,3S,4S,5R,6S)-3,4,6-Trihydroxy-2-Hydroxymethyl-7,9-Diaza-1-Oxa-Spiro[4,5]Decane-10-One-8-Thione is a sophisticated spirocyclic compound featuring a unique heterocyclic scaffold. This molecule matters as a high-value chemical intermediate and pharmacophore for advanced research and development. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers focused on developing novel therapeutics, particularly in areas like enzyme inhibition and targeted drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for complex target molecules.
• Biochemical Research: Used as a precursor or reference standard in medicinal chemistry for studying enzyme-substrate interactions and inhibition mechanisms.
• Chemical Synthesis: Acts as a versatile chiral synthon for constructing complex spirocyclic and heterocyclic frameworks in advanced organic chemistry.
• Academic & Industrial R&D: Employed in discovery programs for new drugs, agrochemicals, and specialty materials due to its unique structural features.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	(2R,3S,4S,5R,6S)-3,4,6-Trihydroxy-2-Hydroxymethyl-7,9-Diaza-1-Oxa-Spiro[4,5]Decane-10-One-8-Thione
CAS No.	227458-60-8
Molecular Formula	C8H12N2O5S
Molecular Weight	248.26 g/mol
Synonyms	7,9-Diaza-1-oxaspiro[4.5]decane-10-one-8-thione, 3,4,6-trihydroxy-2-(hydroxymethyl)-, (2R,3S,4S,5R,6S)-; Spirocyclic thiohydantoin derivative; (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-7,9-diaza-1-oxaspiro[4.5]decane-3,4,6-triol-10-one-8-thione; CAS 227458-60-8; Advanced spiro heterocycle; Chiral spiro[4.5]decane scaffold.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, NMR, and MS for identity confirmation and purity verification. Certificates of Analysis (COA) detailing batch-specific results are available upon request. Our quality management system is designed to support cGMP and ISO guidelines for research and development materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.