Description

Methyl 2-(4-Fluoro-3-Nitrophenyl)Acetate is a high-purity fluorinated aromatic ester building block, essential for advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with specific electronic and steric properties. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the fluorine and nitro functional groups contribute to biological activity.
• Material Science Research: Serves as a monomer or building block for creating specialty polymers and liquid crystals with tailored optical or electronic properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, esterifications, and nucleophilic aromatic substitution reactions to introduce functionalized phenylacetate motifs.
• Chemical Intermediate for Dyes & Pigments: Acts as a starting material for synthesizing complex fluorinated dyes and colorants.

Basic Information

Product Name	Methyl 2-(4-Fluoro-3-Nitrophenyl)Acetate
CAS No.	226888-37-5
Molecular Formula	C9H8FNO4
Molecular Weight	213.16 g/mol
Synonyms	Methyl (4-Fluoro-3-nitrophenyl)acetate; (4-Fluoro-3-nitrophenyl)acetic acid methyl ester; Methyl 2-(4-Fluoro-3-nitrophenyl)ethanoate; 2-(4-Fluoro-3-nitrophenyl)acetic acid methyl ester; Methyl α-(4-fluoro-3-nitrophenyl)acetate; Methyl 4'-Fluoro-3'-nitrophenylacetate; NSC 405124; MFCD03094075
EINECS	Contact for details

Quality Control

Our Methyl 2-(4-Fluoro-3-Nitrophenyl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or kept in secondary opaque packaging.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.