Description

(R)-tert-Butyl 3-((S)-4-Benzyl-2-Oxooxazolidine-3-Carbonyl)Hexanoate is a high-purity chiral building block and advanced pharmaceutical intermediate. Its value lies in its defined stereochemistry, which is critical for synthesizing enantiomerically pure active pharmaceutical ingredients (APIs) with specific biological activity. This compound is essential for research and production in the pharmaceutical industry, particularly for developing novel therapeutics where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug molecules, especially in oncology and central nervous system (CNS) therapeutic areas.
• Asymmetric Synthesis: Used as a precursor or auxiliary in stereoselective reactions to construct molecules with high enantiomeric excess (ee).
• API Development: Serves as a critical building block in the research, development, and scale-up of new chemical entities (NCEs).
• Process Chemistry: Employed in route scouting and optimization for the commercial manufacturing of chiral drugs.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CRMOs) producing bespoke intermediates for clients.
• Academic & Industrial Research: Utilized in medicinal chemistry programs to explore structure-activity relationships (SAR) and develop novel bioactive compounds.

Basic Information

Product Name	(R)-tert-Butyl 3-((S)-4-Benzyl-2-Oxooxazolidine-3-Carbonyl)Hexanoate
CAS No.	225377-55-9
Molecular Formula	C21H29NO5
Molecular Weight	375.46 g/mol
Synonyms	(R)-tert-Butyl 3-((S)-4-benzyl-2-oxooxazolidine-3-carbonyl)hexanoate; tert-Butyl (3R)-3-[(4S)-4-benzyl-2-oxo-1,3-oxazolidine-3-carbonyl]hexanoate; (R)-3-[(S)-4-Benzyl-2-oxo-oxazolidine-3-carbonyl]-hexanoic acid tert-butyl ester; (R)-tert-Butyl 3-((S)-4-benzyl-2-oxooxazolidine-3-carbonyl)hexanoate; (R)-tert-Butyl 3-[(S)-4-benzyl-2-oxooxazolidine-3-carbonyl]hexanoate; (R)-tert-Butyl 3-((S)-4-benzyl-2-oxo-1,3-oxazolidine-3-carbonyl)hexanoate; 225377-55-9; Chiral Oxazolidinone Derivative
EINECS	Contact for details

Quality Control

Our (R)-tert-Butyl 3-((S)-4-Benzyl-2-Oxooxazolidine-3-Carbonyl)Hexanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) with full specifications, including identity (IR, NMR), purity (HPLC), and chiral assay, is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.