Description

1-(4-Hydroxyphenyl)-3-(2-Thienyl)-2-Propen-1-One is a high-purity, synthetic chalcone derivative characterized by its unique molecular structure combining phenolic and thiophene moieties. This compound serves as a critical advanced pharmaceutical intermediate and a versatile organic building block for research and development. It is primarily utilized by manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and material science sectors seeking to develop novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and microbial infections.
• Organic Synthesis Building Block: Used in research to construct more complex heterocyclic compounds and fine chemicals via reactions like cyclization and condensation.
• Agrochemical Research: Serves as a starting material for developing new pesticides and herbicides with enhanced efficacy.
• Material Science: Investigated for use in organic semiconductors, nonlinear optical (NLO) materials, and photonic applications due to its conjugated system.
• Biochemical Research: Used as a standard or probe in studies related to enzyme inhibition and biological activity screening.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing specialty aroma chemicals.

Basic Information

Item	Detail
Product Name	1-(4-Hydroxyphenyl)-3-(2-Thienyl)-2-Propen-1-One
CAS No.	224638-42-0
Molecular Formula	C13H10O2S
Molecular Weight	230.28 g/mol
Synonyms	3-(2-Thienyl)-1-(4-hydroxyphenyl)-2-propen-1-one; 4'-Hydroxy-2-thienylchalcone; 1-(4-Hydroxyphenyl)-3-(thiophen-2-yl)prop-2-en-1-one; 2-Thienyl-4'-hydroxychalcone; (E)-1-(4-Hydroxyphenyl)-3-(thiophen-2-yl)prop-2-en-1-one; 4-Hydroxy-3-(2-thienyl)-1-phenyl-2-propen-1-one; Chalcone derivative, Thiophene chalcone
EINECS	Contact for details

Quality Control

Our 1-(4-Hydroxyphenyl)-3-(2-Thienyl)-2-Propen-1-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic methods (IR, NMR) for structural confirmation, to ensure it meets precise customer specifications. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.