Description

(3-Fluoro-4-(Morpholinyl)Phenyl)Isocyanate is a specialized aromatic isocyanate building block featuring a fluorine substituent and a morpholine ring. This compound matters for its role as a key intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where its unique structure enables the introduction of specific pharmacophores. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other targeted therapy research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the fluorine and morpholine groups enhance biological activity and environmental stability.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the production of specialty polyurethanes and polyurea coatings with tailored properties.
• Material Science Research: Employed in the creation of advanced functional materials, including liquid crystals and organic semiconductors.
• Bioconjugation & Probe Development: Utilized for labeling biomolecules or creating fluorescent probes and other diagnostic tools due to its reactive isocyanate group.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom chemical synthesis services catering to diverse R&D projects.

Basic Information

Product Name	(3-Fluoro-4-(Morpholinyl)Phenyl)Isocyanate
CAS No.	224323-51-7
Molecular Formula	C11H11FN2O2
Molecular Weight	222.22 g/mol
Synonyms	3-Fluoro-4-morpholinophenyl isocyanate; 4-Isocyanato-2-fluoro-1-morpholinobenzene; 1-Fluoro-2-isocyanato-4-morpholinobenzene; 2-Fluoro-4-morpholinophenyl isocyanate; (4-Morpholino-3-fluorophenyl) isocyanate; 3-Fluoro-4-morpholino-1-isocyanatobenzene; 4-(3-Fluoro-4-isocyanatophenyl)morpholine
EINECS	Contact for details

Quality Control

Our (3-Fluoro-4-(Morpholinyl)Phenyl)Isocyanate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.