Description

2,2',3,3'-Tetrahydro-1,1'-Spirobi[1H-Indene]-7,7'-Diol is a specialized organic compound belonging to the class of spirocyclic diols, serving as a crucial chiral building block and intermediate in advanced organic synthesis. Its rigid, three-dimensional spirobiindane structure makes it highly valuable for constructing complex molecular architectures with precise stereochemistry. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), asymmetric catalysts, and high-performance materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in areas requiring complex, stereodefined cores.
• Asymmetric Catalyst Ligand Precursor: Used to develop sophisticated ligands for transition metal catalysis, enabling highly enantioselective reactions.
• Advanced Material Research: Serves as a monomer or building block for creating polymers and organic frameworks with unique optical or mechanical properties.
• Academic & R&D Laboratories: Employed in methodological studies and the discovery of new synthetic pathways in organic chemistry.
• Fine Chemical Synthesis: Integral for the production of specialty chemicals where its specific stereochemistry imparts desired functionality.

Basic Information

Product Name	2,2',3,3'-Tetrahydro-1,1'-Spirobi[1H-Indene]-7,7'-Diol
CAS No.	223137-87-9
Molecular Formula	C17H16O2
Molecular Weight	252.31 g/mol
Synonyms	7,7'-Dihydroxy-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-indene]; 1,1'-Spirobi[1H-indene]-7,7'-diol, 2,2',3,3'-tetrahydro-; Spirobiindane-7,7'-diol; 7,7'-Dihydroxyspirobiindane; (R/S)-2,2',3,3'-Tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol; CAS 223137-87-9
EINECS	Contact for details

Quality Control

Our production of 2,2',3,3'-Tetrahydro-1,1'-Spirobi[1H-Indene]-7,7'-Diol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and potential degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.