Description

(3-Bromo-2-Methyl-Phenyl)-Carbamic Acid tert-Butyl Ester is a high-purity, protected aniline derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the controlled introduction of a brominated, methyl-substituted aromatic amine moiety into complex molecular architectures. It is primarily needed by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting new small molecule therapies.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Organic Synthesis Reagent: Serves as a protected amine precursor in multi-step synthetic routes, including cross-coupling reactions and functional group transformations.
• Chemical Research & Development: Essential for academic and industrial R&D labs exploring new chemical reactions and synthesizing complex organic molecules for material science.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for fine chemical manufacturers producing bespoke compounds for client projects.

Basic Information

Product Name	(3-Bromo-2-Methyl-Phenyl)-Carbamic Acid tert-Butyl Ester
CAS No.	221538-03-0
Molecular Formula	C12H16BrNO2
Molecular Weight	286.17 g/mol
Synonyms	tert-Butyl (3-bromo-2-methylphenyl)carbamate; N-Boc-3-bromo-2-methylaniline; N-(tert-Butoxycarbonyl)-3-bromo-2-methylaniline; 3-Bromo-2-methylphenylcarbamic acid tert-butyl ester; BOC-3-Bromo-2-methylaniline; 1-Bromo-2-methyl-3-((tert-butoxycarbonyl)amino)benzene; (3-Bromo-o-tolyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our (3-Bromo-2-Methyl-Phenyl)-Carbamic Acid tert-Butyl Ester is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.