Description

Spiro[3.5]Nonane-6,8-Dione is a high-purity, specialized spirocyclic diketone building block of significant interest in advanced organic synthesis. Its unique rigid, three-dimensional structure makes it a valuable precursor for constructing complex molecular architectures, particularly in pharmaceutical and materials science research. This compound is essential for chemists and R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking novel scaffolds for drug discovery and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key spirocyclic scaffold in the synthesis of potential active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where its rigid structure can impart unique biological activity and stability.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer and Material Science: Employed as a monomer or cross-linking agent to create polymers with specific thermal and mechanical properties.
• Chemical Biology Probe Synthesis: Utilized to build molecular probes for studying enzyme function and biological pathways.
• Academic and Industrial R&D: A fundamental building block for methodological development in organic chemistry and the exploration of new chemical space.

Basic Information

Product Name	Spiro[3.5]Nonane-6,8-Dione
CAS No.	221342-48-9
Molecular Formula	C9H12O2
Molecular Weight	152.19 g/mol
Synonyms	6,8-Dioxaspiro[3.5]nonane; 6,8-Dioxaspiro(3.5)nonane; Spiro[3.5]nonane-6,8-dione; 1,4-Dioxaspiro[4.2]heptane-5,7-dione (tautomeric form); 6,8-Dioxaspiro[3.5]nonan; 221342-48-9; Spiro-3,5-nonane-6,8-dione
EINECS	Contact for details

Quality Control

Our Spiro[3.5]Nonane-6,8-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity building blocks for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Specification available upon request
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.