Description

2-Fluoro-4-isocyanato-1-methoxybenzene (Saltdata: Free) is a specialized aromatic isocyanate derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity of the isocyanate group combined with the electronic influence of the fluorine and methoxy substituents, enabling precise molecular construction. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Polymer & Material Science: Serves as a monomer or cross-linking agent in the development of specialty polyurethanes, coatings, and adhesives with tailored properties.
• Chemical Research & Development: A versatile reagent for constructing complex heterocycles and functionalized aromatic compounds in academic and industrial R&D labs.
• Liquid Crystal & OLED Material Precursor: Used in the synthesis of fluorinated aromatic components for electronic display and lighting technologies.

Basic Information

Product Name	2-Fluoro-4-isocyanato-1-methoxybenzene (Saltdata: Free)
CAS No.	221218-33-3
Molecular Formula	C8H6FNO2
Molecular Weight	167.14 g/mol
Synonyms	1-Fluoro-2-methoxy-5-isocyanatobenzene; 4-Fluoro-3-isocyanatoanisole; 2-Fluoro-4-isocyanatoanisole; 5-Isocyanato-2-fluoroanisole; 3-Methoxy-4-fluorophenyl isocyanate; 2-Fluoro-4-methoxyphenyl isocyanate; 2-Fluoro-4-isocyanato-1-methoxybenzene (Free Base)
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-isocyanato-1-methoxybenzene is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.