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2-Amino-7-Methyl-5-Oxo-4-[4-(Propan-2-Yl)Phenyl]-4H,5H-Pyrano[4,3-B]Pyran-3-Carbonitrile CAS NO 220986-28-7


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CAS No.:220986-28-7

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Description

2-Amino-7-Methyl-5-Oxo-4-[4-(Propan-2-Yl)Phenyl]-4H,5H-Pyrano[4,3-B]Pyran-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate with a complex fused pyranopyran structure. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), enabling research and development in new therapeutic areas. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on medicinal chemistry and heterocyclic compound synthesis.

Application

  • Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates targeting various disease pathways.
  • Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
  • Fine Chemical Synthesis: Employed in multi-step organic syntheses to construct complex molecular architectures for specialty chemicals.
  • Academic & Institutional R&D: Utilized in universities and research institutes for studying heterocyclic chemistry and developing new synthetic methodologies.
  • Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the life sciences industry.

Basic Information

Product Name 2-Amino-7-Methyl-5-Oxo-4-[4-(Propan-2-Yl)Phenyl]-4H,5H-Pyrano[4,3-B]Pyran-3-Carbonitrile
CAS No. 220986-28-7
Molecular Formula C19H18N2O3
Molecular Weight 322.36 g/mol
Synonyms 2-Amino-7-methyl-5-oxo-4-(4-isopropylphenyl)-4H,5H-pyrano[4,3-b]pyran-3-carbonitrile; 4-(4-Isopropylphenyl)-2-amino-7-methyl-5-oxo-4H,5H-pyrano[4,3-b]pyran-3-carbonitrile; 2-Amino-4-(4-isopropylphenyl)-7-methyl-5-oxo-4H,5H-pyrano[4,3-b]pyran-3-carbonitrile; Pyrano[4,3-b]pyran-3-carbonitrile, 2-amino-7-methyl-5-oxo-4-[4-(1-methylethyl)phenyl]-4H,5H-; CAS 220986-28-7
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Quality Control

Our 2-Amino-7-Methyl-5-Oxo-4-[4-(Propan-2-Yl)Phenyl]-4H,5H-Pyrano[4,3-B]Pyran-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and development use. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item Specification
Appearance Off-white to light yellow crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Loss on Drying ≤ 1.0%
Residue on Ignition ≤ 0.5%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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