Description

(R)-tert-Butyl 3-Hydroxypent-4-Enoate is a high-purity chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its value lies in its well-defined stereochemistry and functional group array, enabling the precise construction of complex molecular architectures. This compound is primarily needed by research and development laboratories, as well as production facilities, in the pharmaceutical and fine chemical industries for applications such as asymmetric synthesis and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of potential drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Utilized as a building block for constructing complex molecules with defined stereocenters in medicinal chemistry.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, flavors, and fragrances requiring specific enantiomeric purity.
• Academic & Industrial Research: Used in methodological development and exploratory synthesis within organic chemistry R&D.
• Process Chemistry: Evaluated for scale-up in the development of efficient and cost-effective synthetic routes.

Basic Information

Product Name	(R)-tert-Butyl 3-Hydroxypent-4-Enoate
CAS No.	220861-37-0
Molecular Formula	C9H16O3
Molecular Weight	172.22 g/mol
Synonyms	(R)-3-Hydroxy-4-pentenoic acid tert-butyl ester; tert-Butyl (3R)-3-hydroxypent-4-enoate; (R)-tert-Butyl 3-hydroxy-4-pentenoate; (R)-3-Hydroxypent-4-enoic acid tert-butyl ester; (R)-tert-Butyl 3-hydroxypent-4-enoate; (3R)-3-Hydroxy-4-pentenoic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our (R)-tert-Butyl 3-Hydroxypent-4-Enoate is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes rigorous analytical testing, including chiral HPLC, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.