Description

(R)-2-Cyclohexyl Succinic Acid-1-Methyl Ester is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry and functional group versatility make it a critical building block for producing enantiomerically pure compounds. This product is essential for research and development chemists and process engineers in the pharmaceutical and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and complex specialty molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure Active Pharmaceutical Ingredients (APIs) and drug candidates.
• Asymmetric Synthesis: Used as a building block in stereoselective reactions to construct complex molecular architectures with high optical purity.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, catalysts, and ligands for organic transformations.
• Agrochemical Research: Employed in the development of chiral pesticides and herbicides where specific stereochemistry impacts biological activity.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and process chemistry optimization.
• Material Science: Potential use as a monomer or modifier in the synthesis of specialized polymers with tailored properties.

Basic Information

Product Name	(R)-2-Cyclohexyl Succinic Acid-1-Methyl Ester
CAS No.	220498-07-7
Molecular Formula	C11H18O4
Molecular Weight	214.26 g/mol
Synonyms	(R)-1-Methoxy-1-oxo-2-(cyclohexyl)butanedioate; (R)-Methyl 2-cyclohexylsuccinate; (R)-Cyclohexylsuccinic Acid Monomethyl Ester; (2R)-2-Cyclohexylbutanedioic Acid 1-Methyl Ester; (R)-2-(Cyclohexyl)succinic Acid Methyl Ester; (R)-Methyl Hydrogen 2-Cyclohexylsuccinate; (R)-2-Cyclohexyl-1-methoxy-1,4-dioxobutane-4-carboxylate
EINECS	Contact for details

Quality Control

Our (R)-2-Cyclohexyl Succinic Acid-1-Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.