Description

(S)-2-(2-Naphthylmethyl)Succinic Acid-1-Methyl Ester is a high-purity chiral building block and synthetic intermediate of significant commercial importance. Its value lies in its defined stereochemistry and functional groups, which are critical for constructing complex molecules with specific biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel therapeutic agents, including enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where stereoselectivity impacts efficacy and environmental safety.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the study and development of new asymmetric catalytic processes.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	(S)-2-(2-Naphthylmethyl)Succinic Acid-1-Methyl Ester
CAS No.	220497-75-6
Molecular Formula	C₁₆H₁₆O₄
Molecular Weight	272.30 g/mol
Synonyms	(S)-1-Methyl 2-(2-naphthylmethyl)succinate; (S)-Methyl 2-((naphthalen-2-yl)methyl)succinate; (S)-2-(2-Naphthylmethyl)butanedioic acid 1-methyl ester; Succinic acid, 2-(2-naphthylmethyl)-, 1-methyl ester, (S)-; (2S)-2-[(Naphthalen-2-yl)methyl]-4-methoxy-4-oxobutanoic acid
EINECS	Contact for details

Quality Control

Our production of (S)-2-(2-Naphthylmethyl)Succinic Acid-1-Methyl Ester adheres to stringent quality management protocols. Every batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting customer and research-grade specifications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.