Description

(S)-2-(Cyclohexylmethyl)Succinic Acid-1-Methyl Ester is a high-purity chiral building block and synthetic intermediate of significant commercial interest. This compound is valued for its defined stereochemistry and functional group versatility, enabling the synthesis of complex molecules with high enantiomeric purity. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis and active pharmaceutical ingredient (API) development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for constructing specific stereocenters.
• Asymmetric Synthesis: Used as a starting material or intermediate in catalytic asymmetric reactions to produce enantiomerically enriched compounds.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, agrochemicals, and advanced materials requiring precise molecular architecture.
• Academic & Industrial Research: Serves as a valuable reagent in methodological studies and process chemistry optimization within R&D laboratories.
• Peptidomimetics & Bioactive Molecule Synthesis: Its structure makes it suitable for incorporation into peptide analogs and other bioactive compound libraries.

Basic Information

Product Name	(S)-2-(Cyclohexylmethyl)Succinic Acid-1-Methyl Ester
CAS No.	220497-69-8
Molecular Formula	C12H20O4
Molecular Weight	228.29 g/mol
Synonyms	(S)-1-Methyl 2-(cyclohexylmethyl)succinate; (S)-2-(Cyclohexylmethyl)butanedioic acid 1-methyl ester; Methyl (S)-2-(cyclohexylmethyl)succinate; (2S)-2-(Cyclohexylmethyl)butanedioic acid methyl ester; Succinic acid, 2-(cyclohexylmethyl)-, 1-methyl ester, (S)-; (S)-Methyl 2-(cyclohexylmethyl)succinate; (S)-2-Cyclohexylmethyl-succinic acid methyl ester
EINECS	Contact for details

Quality Control

We supply (S)-2-(Cyclohexylmethyl)Succinic Acid-1-Methyl Ester in high-purity grades suitable for research and commercial synthesis. Our products undergo rigorous quality testing, including chiral purity analysis (HPLC, Chiral GC), to ensure compliance with stringent industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with each batch to guarantee traceability and performance consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC/GC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.