Description

Propanoic Acid, 3,3'-[[2-[(2-Carboxyethoxy)Methyl]-2-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-1,3-Propanediyl]Bis(Oxy)]Bis- is a specialized, high-purity chemical intermediate featuring a complex, multifunctional structure. This compound is valued for its role as a key building block in advanced organic synthesis, particularly in the development of pharmaceuticals and sophisticated polymers. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers for creating novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, especially those requiring specific peptide-like or ester linkages.
• Polymer Chemistry: Used as a monomer or cross-linking agent for producing specialty polymers with tailored properties such as biodegradability or specific reactivity.
• Bioconjugation Reagent: Employed in the development of antibody-drug conjugates (ADCs) and other biopharmaceuticals due to its reactive carboxyl and protected amino groups.
• Chemical Research: Serves as a valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Applied in the creation of advanced coatings, hydrogels, and other functional materials where controlled degradation or specific molecular interactions are required.
• Prodrug Synthesis: Utilized in designing prodrugs where the tert-butoxycarbonyl (Boc) protected amine and carboxylic acid functionalities allow for controlled release mechanisms.

Basic Information

Item	Details
Product Name	Propanoic Acid, 3,3'-[[2-[(2-Carboxyethoxy)Methyl]-2-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-1,3-Propanediyl]Bis(Oxy)]Bis-
CAS No.	220431-61-8
Molecular Formula	C21H35NO12
Molecular Weight	493.51 g/mol
Synonyms	3,3'-[[2-[(2-Carboxyethoxy)methyl]-2-[[(1,1-dimethylethoxy)carbonyl]amino]-1,3-propanediyl]bis(oxy)]bispropanoic acid; Bis(carboxyethyl) ether derivative; Boc-protected triacid linker; 2,2',2''-Nitrilotris(ethane-2,1-diyl)tris(oxy)tris(propanoic acid) tert-butyl ester (related); ADC linker precursor; Multifunctional carboxylic acid derivative; Polyethylene glycol triacid analog; TFA salt precursor (common derivative).
EINECS	Contact for details

Quality Control

Our Propanoic Acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content to ensure compliance with exacting R&D and production standards. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for every shipment, ensuring full traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.