Description

3-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]-1-Propanol, 4-Nitrobenzenesulfonate is a specialized organosilicon-protected intermediate with a sulfonate ester leaving group, designed for high-value synthetic chemistry. This compound is critical for researchers and manufacturers requiring precise, moisture-sensitive functional group manipulation under mild conditions. It is primarily utilized in the pharmaceutical and advanced organic synthesis sectors for the controlled introduction of protected alcohol functionalities and as a precursor in multi-step synthetic routes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those requiring silyl-protected propanol derivatives.
• Nucleoside & Nucleotide Chemistry: Used in the protection and activation steps for the synthesis of modified nucleosides and nucleotides.
• Peptide & Oligosaccharide Synthesis: Serves as a reagent for introducing protecting groups or as a linker in solid-phase synthesis.
• Polymer & Material Science: Acts as a functional monomer or cross-linking agent for creating specialty polymers with specific surface properties.
• Agrochemical Synthesis: Employed in the development of advanced active ingredients that require selective protection-deprotection strategies.
• Chemical Research & Development: A valuable tool for academic and industrial R&D labs exploring new synthetic methodologies involving silyl ethers and sulfonate esters.

Basic Information

Item	Details
Product Name	3-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]-1-Propanol, 4-Nitrobenzenesulfonate
CAS No.	220299-14-9
Molecular Formula	C15H25NO6SSi
Molecular Weight	375.52 g/mol
Synonyms	3-[(tert-Butyldimethylsilyl)oxy]-1-propanol 4-nitrobenzenesulfonate; 3-(TBDMS-oxy)-1-propanol nosylate; 3-(tert-Butyldimethylsiloxy)propan-1-ol 4-nitrobenzenesulfonate; 1-Propanol, 3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, 4-nitrobenzenesulfonate; TBDMS-protected propanol nosylate; Nosyl ester of 3-(TBDMSO)propanol; 3-Hydroxypropyl tert-butyldimethylsilyl ether 4-nitrobenzenesulfonate
EINECS	Contact for details

Quality Control

Our production of 3-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]-1-Propanol, 4-Nitrobenzenesulfonate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.