Description

L-Serine, n-(1-Methylethyl)-, Methyl Ester (9Ci) is a specialized, non-proteinogenic serine derivative. This compound is a valuable chiral building block and intermediate in organic synthesis, prized for its role in constructing complex molecules with defined stereochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), peptides, and fine chemicals. Its defined structure makes it essential for applications requiring high-purity, custom-tailored intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs) and therapeutic peptides.
• Peptide Synthesis: Used as a protected serine derivative in solid-phase and solution-phase peptide chemistry to introduce specific functionalities.
• Agrochemical Research: Serves as a precursor in the synthesis of advanced, biologically active compounds for crop protection.
• Chemical Biology & Proteomics: Employed in the design and synthesis of enzyme inhibitors, probes, and modified amino acids for mechanistic studies.
• Fine Chemical Synthesis: Acts as a versatile building block for creating complex natural product analogs and specialty chemicals.
• Academic & Industrial R&D: Essential for methodological development in asymmetric synthesis and medicinal chemistry projects.

Basic Information

Product Name	L-Serine, n-(1-Methylethyl)-, Methyl Ester (9Ci)
CAS No.	220280-32-0
Molecular Formula	C7H15NO3
Molecular Weight	161.20 g/mol
Synonyms	L-Serine, N-isopropyl-, methyl ester; Methyl N-isopropyl-L-serinate; (2S)-2-[(Propan-2-yl)amino]-3-hydroxypropanoic acid methyl ester; L-Serine, N-(1-methylethyl)-, methyl ester; Serine, N-isopropyl-, methyl ester, L-; N-Isopropyl-L-serine methyl ester; Methyl (S)-2-(isopropylamino)-3-hydroxypropanoate
EINECS	Contact for details

Quality Control

We supply L-Serine, n-(1-Methylethyl)-, Methyl Ester (9Ci) in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We adhere to a robust quality management system to support your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.