Description

Phenol, 4-Isocyanato-3-(Trifluoromethyl)- (9Ci) is a specialized aromatic isocyanate derivative, distinguished by the presence of a reactive isocyanate group and a trifluoromethyl substituent. This molecular architecture makes it a high-value building block for synthesizing advanced materials with enhanced chemical resistance and tailored surface properties. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for creating novel compounds and functional coatings.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for introducing the trifluoromethylphenyl moiety into active pharmaceutical ingredients (APIs), potentially enhancing metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the trifluoromethyl group contributes to improved efficacy and environmental profile.
• Specialty Polyurethane & Polyurea Precursor: Acts as a reactive monomer for formulating high-performance coatings, adhesives, and elastomers with superior chemical and thermal resistance.
• Liquid Crystal & OLED Material Development: Employed in the research and manufacture of electronic display components and organic light-emitting diodes (OLEDs).
• Cross-linking Agent for Polymers: Functions as a cross-linker in resin systems to improve mechanical strength, adhesion, and durability.
• Surface Modification Reagent: Used to graft specific functional groups onto material surfaces, altering wettability, adhesion, and biocompatibility.

Basic Information

Product Name	Phenol, 4-Isocyanato-3-(Trifluoromethyl)- (9Ci)
CAS No.	220239-70-3
Molecular Formula	C8H4F3NO2
Molecular Weight	203.12 g/mol
Synonyms	4-Isocyanato-3-(trifluoromethyl)phenol; 3-(Trifluoromethyl)-4-hydroxyphenyl isocyanate; 4-Hydroxy-2-(trifluoromethyl)phenyl isocyanate; 2-Trifluoromethyl-4-hydroxyphenyl isocyanate; 3-Trifluoromethyl-4-isocyanatophenol; 4-Isocyanato-alpha,alpha,α-trifluoro-m-cresol; m-Cresol, 4-isocyanato-alpha,alpha,α-trifluoro- (8CI)
EINECS	Contact for details

Quality Control

Our production of Phenol, 4-Isocyanato-3-(Trifluoromethyl)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical synthesis. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP and ISO 9001 compliant manufacturing environments, and specifications can be tailored to meet the rigorous demands of pharmaceutical and advanced material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation of the isocyanate functionality. Keep away from heat, sparks, open flames, and incompatible materials such as alcohols, amines, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.