Description

(3β)-Cholesta-5,24-Dien-3-YloxyDimethylsilane is a high-purity, sterol-derived silyl ether compound, serving as a crucial protected intermediate in advanced organic synthesis. Its value lies in providing a robust, lipophilic protecting group for sensitive hydroxyl functionalities, enabling complex multi-step reactions in controlled environments. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly those developing novel steroid-based therapeutics, bioactive molecules, and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key protected intermediate in the synthesis of novel steroid drugs, hormone analogs, and other bioactive sterol derivatives.
• Fine Chemical Synthesis: Used in multi-step organic synthesis to protect hydroxyl groups during reactions with strong bases, oxidizing agents, or other incompatible reagents.
• Research & Development: Critical for academic and industrial R&D labs exploring new synthetic pathways for complex natural products and molecular scaffolds.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for high-value target molecules requiring selective protection/deprotection strategies.
• Reference Standard: Serves as a certified reference material (CRM) or analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(3β)-Cholesta-5,24-Dien-3-YloxyDimethylsilane
CAS No.	220150-72-1
Molecular Formula	C33H58OSi
Molecular Weight	498.90 g/mol
Synonyms	(3β)-Cholesta-5,24-dien-3-ol TBDMS ether; tert-Butyldimethylsilyl (3β)-cholesta-5,24-dien-3-yl ether; TBDMS ether of (3β)-Cholesta-5,24-dien-3-ol; 3β-(tert-Butyldimethylsilyloxy)cholesta-5,24-diene; Sterol TBDMS ether; Cholestadienyl tert-butyldimethylsilyl ether; (3β)-3-[(tert-Butyldimethylsilyl)oxy]cholesta-5,24-diene
EINECS	Contact for details

Quality Control

Our (3β)-Cholesta-5,24-Dien-3-YloxyDimethylsilane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.