Description

Spiro[1-Azabicyclo[2.2.2]Octane-3,2'(3'H)-Furo[2,3-B]Pyridine] is a complex spirocyclic organic compound featuring a fused furopyridine and quinuclidine-like structure, serving as a sophisticated chemical building block. This compound is valued for its unique three-dimensional architecture, which is critical for modulating biological activity and physical properties in advanced research. It is primarily sought by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, particularly in central nervous system (CNS) and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Key precursor in the research and development of novel drug candidates, especially those targeting neurological receptors.
• Agrochemical Synthesis: Used in creating advanced active ingredients for crop protection products with specific mode-of-action requirements.
• Chemical Biology Probe: Serves as a core scaffold for developing molecular probes to study enzyme and receptor function.
• Material Science Research: Investigated as a building block for specialty polymers or ligands in catalytic systems due to its rigid, complex geometry.
• Academic & Contract Research: Essential for synthetic chemistry research in universities and CROs (Contract Research Organizations) exploring new heterocyclic methodologies.

Basic Information

Product Name	Spiro[1-Azabicyclo[2.2.2]Octane-3,2'(3'H)-Furo[2,3-B]Pyridine]
CAS No.	220099-89-8
Molecular Formula	C13H14N2O
Molecular Weight	214.26 g/mol
Synonyms	Spiro[furo[2,3-b]pyridine-3(2H),3'-quinuclidine]; 2'H-Spiro[furo[2,3-b]pyridine-3,3'-quinuclidine]; Furo[2,3-b]pyridine, 2,3-dihydro-2,2'-spirobi-1-azabicyclo[2.2.2]octane; Spiro(quinuclidine-3,2'(3'H)-furo[2,3-b]pyridine); 1-Azabicyclo[2.2.2]octane, spiro[furo[2,3-b]pyridine-3(2H),3'-(1'-azabicyclo[2.2.2]octane)]
EINECS	Contact for details

Quality Control

Our Spiro[1-Azabicyclo[2.2.2]Octane-3,2'(3'H)-Furo[2,3-B]Pyridine] is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.