Description

Methyl 5-(Benzyloxy)Nicotinate is a high-purity synthetic intermediate of significant importance in advanced organic synthesis. Its core value lies in its role as a versatile building block for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for API synthesis and novel compound libraries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing nicotinic acid or pyridine derivatives.
• Medicinal Chemistry Research: Serves as a crucial building block for constructing novel chemical entities and compound libraries for drug discovery programs targeting various diseases.
• Agrochemical Synthesis: Used in the development and production of advanced crop protection agents and herbicides.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organocatalysts for asymmetric synthesis.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fine chemicals and specialty materials.
• Academic and R&D Laboratories: Utilized in university and institutional research for methodological development and exploratory synthesis.

Basic Information

Product Name	Methyl 5-(Benzyloxy)Nicotinate
CAS No.	219817-42-2
Molecular Formula	C14H13NO3
Molecular Weight	243.26 g/mol
Synonyms	5-(Benzyloxy)nicotinic acid methyl ester; Methyl 5-benzyloxynicotinate; 3-Pyridinecarboxylic acid, 5-(phenylmethoxy)-, methyl ester; Nicotinic acid, 5-(benzyloxy)-, methyl ester; Methyl 5-(phenylmethoxy)nicotinate; 5-Benzyloxy-nicotinic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-(Benzyloxy)Nicotinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.