Description

(S)-3-Amino-3-(4-Tolyl)Propionic Acid Ethyl Ester is a high-purity, single-enantiomer chiral building block of significant importance in modern synthetic chemistry. This compound is valued for its role as a key intermediate in the synthesis of complex, biologically active molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active pharmaceutical ingredients (APIs) and other specialty compounds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the asymmetric synthesis of drug candidates, particularly those targeting neurological and metabolic disorders.
• API Synthesis: Used in the construction of complex molecular scaffolds for potential Active Pharmaceutical Ingredients (APIs).
• Agrochemical Research: Serves as a building block for developing novel, enantiomerically pure pesticides and herbicides.
• Peptidomimetics: Incorporated into the design of peptide analogs and mimetics for medicinal chemistry applications.
• Ligand and Catalyst Development: Utilized as a precursor for chiral ligands and organocatalysts used in asymmetric transformations.
• Academic & Industrial R&D: Essential for methodological development and discovery chemistry in both academic laboratories and corporate R&D centers.

Basic Information

Product Name	(S)-3-Amino-3-(4-Tolyl)Propionic Acid Ethyl Ester
CAS No.	219813-90-8
Molecular Formula	C12H17NO2
Molecular Weight	207.27 g/mol
Synonyms	(S)-Ethyl 3-amino-3-(p-tolyl)propanoate; (S)-3-Amino-3-(4-methylphenyl)propanoic acid ethyl ester; Ethyl (S)-3-amino-3-(4-methylphenyl)propanoate; (S)-Ethyl 3-amino-3-(4-methylphenyl)propionate; (S)-3-Amino-3-p-tolyl-propionic acid ethyl ester; (S)-AATE; (S)-3-Amino-3-(4-tolyl)propanoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our (S)-3-Amino-3-(4-Tolyl)Propionic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.