Description

Cyclopropanecarboxylic Acid, Methylene-, 1,1-Dimethylethyl Ester (9Ci) is a specialized organic ester building block, valued for its unique strained cyclopropane ring system and the tert-butyl ester protecting group. This compound is essential for advanced organic synthesis, particularly in pharmaceutical research and development, where it serves as a key intermediate for constructing complex molecular architectures. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or possessing complex stereochemistry.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides and herbicides, where the cyclopropane moiety can impart specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Investigated as a monomer or additive for developing polymers with unique thermal or mechanical properties due to the strained ring structure.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, Methylene-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	219788-08-6
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	tert-Butyl 2-methylenecyclopropanecarboxylate; 2-Methylenecyclopropanecarboxylic acid tert-butyl ester; tert-Butyl 2-methylidenecyclopropane-1-carboxylate; (2-Methylenecyclopropyl)carboxylic acid tert-butyl ester; 1,1-Dimethylethyl 2-methylene-1-cyclopropanecarboxylate; 2-Methylenecyclopropanecarboxylic Acid 1,1-Dimethylethyl Ester
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, Methylene-, 1,1-Dimethylethyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure high purity and consistent performance for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.