Description

Methyl (R)-2-Amino-4-Bromobutyrate CAS NO 219752-67-7 is a chiral, non-natural amino acid ester derivative that serves as a critical building block in organic synthesis. Its value lies in its dual functionality, featuring both a protected amino group and a reactive bromoalkyl side chain, enabling its use in the construction of complex, biologically active molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, enzyme modulators, and other small molecule therapeutics.
• Peptidomimetics Research: Used to incorporate unnatural amino acid residues into peptide chains to enhance metabolic stability and biological activity.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced herbicides and plant growth regulators.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create labeled or modified amino acids for studying biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring specific chiral centers and functional group transformations.

Basic Information

Product Name	Methyl (R)-2-Amino-4-Bromobutyrate
CAS No.	219752-67-7
Molecular Formula	C5H10BrNO2
Molecular Weight	196.04 g/mol
Synonyms	(R)-Methyl 2-Amino-4-bromobutanoate; (R)-Methyl 4-Bromo-2-aminobutanoate; (2R)-2-Amino-4-bromobutanoic Acid Methyl Ester; D-Methyl 2-Amino-4-bromobutyrate; Methyl (R)-4-Bromo-2-aminobutyrate; (R)-2-Amino-4-bromobutyric Acid Methyl Ester; Methyl (2R)-2-Amino-4-bromobutanoate
EINECS	Contact for details

Quality Control

Our production of Methyl (R)-2-Amino-4-Bromobutyrate adheres to stringent quality management protocols. Each batch is characterized and tested to ensure high chiral purity and chemical integrity, meeting the exacting standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), chiral excess, and impurity profile is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.