Description

(3R,4R)-2,5-Dioxotetrahydrofuran-3,4-Diyl Diacetate is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic utility. This compound is valued for its role in the stereoselective synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for creating optically pure compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of nucleoside analogs, antiviral drugs, and other bioactive molecules requiring specific stereochemistry.
• Asymmetric Synthesis: Used as a precursor or auxiliary in catalytic asymmetric reactions to construct complex molecular architectures with high enantiomeric purity.
• Agrochemical Research: Serves as a building block for developing novel, stereospecific pesticides and herbicides.
• Academic & Process R&D: Employed in research laboratories for method development and scaling up synthetic routes for chiral targets.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals where precise stereocontrol is essential.

Basic Information

Product Name	(3R,4R)-2,5-Dioxotetrahydrofuran-3,4-Diyl Diacetate
CAS No.	219706-58-8
Molecular Formula	C10H12O8
Molecular Weight	260.20 g/mol
Synonyms	(3R,4R)-3,4-Diacetoxy-2,5-dihydrofuran-2,5-dione; (3R,4R)-Tetrahydro-2,5-dioxofuran-3,4-diyl diacetate; (3R,4R)-2,5-Dioxo-tetrahydro-furan-3,4-diyl diacetate; (3R,4R)-3,4-Diacetoxy-dihydrofuran-2,5-dione; L-Threitol 1,4-Diacetate 2,3-Carbonate; (3R,4R)-Di-O-acetyl-L-tartaric anhydride; (3R,4R)-Dioxolane-3,4-diyl diacetate derivative
EINECS	Contact for details

Quality Control

Our (3R,4R)-2,5-Dioxotetrahydrofuran-3,4-Diyl Diacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.