Description

2H-Pyran-3-Methanol, Tetrahydro-, 3-Benzoate, (3S)- is a chiral, high-purity chemical intermediate of significant interest in advanced organic synthesis. Its value lies in its defined stereochemistry and functional groups, which make it a versatile building block for constructing complex molecular architectures. This compound is primarily needed by research institutions and industrial R&D departments in the pharmaceutical and fine chemical sectors for the development of new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral targets.
• Asymmetric Synthesis: Utilized as a building block in stereoselective synthesis to introduce the tetrahydro-2H-pyran moiety with defined (S)-configuration.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where high purity and specific stereochemistry are required.
• Academic & Industrial Research: Used in chemical biology and medicinal chemistry programs to explore structure-activity relationships (SAR).

Basic Information

Product Name	2H-Pyran-3-Methanol, Tetrahydro-, 3-Benzoate, (3S)-
CAS No.	219701-50-5
Molecular Formula	C13H16O3
Molecular Weight	220.26 g/mol
Synonyms	(3S)-Tetrahydro-2H-pyran-3-ylmethyl benzoate; (S)-Tetrahydro-2H-pyran-3-ylmethyl benzoate; (3S)-3-(Hydroxymethyl)tetrahydro-2H-pyran-3-yl benzoate; (S)-Tetrahydro-2H-pyran-3-yl methylbenzoate; Benzoic acid (3S)-tetrahydro-2H-pyran-3-ylmethyl ester; (S)-3-(Benzoyloxymethyl)tetrahydro-2H-pyran; (S)-Tetrahydro-2H-pyran-3-ylmethyl benzoate
EINECS	Contact for details

Quality Control

Our production of (3S)-Tetrahydro-2H-pyran-3-ylmethyl benzoate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral HPLC to ensure enantiomeric purity and identity confirmation by IR and NMR spectroscopy. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is stable under inert atmosphere. Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.