Description

7-Oxa-1-Azaspiro[4.4]Nonane-2,6-Dione,(5R)-(9Ci) is a high-value, stereochemically defined spirocyclic building block used in advanced organic synthesis. This compound is critical for the development of novel pharmaceuticals and agrochemicals due to its rigid, three-dimensional structure which can impart unique biological activity and metabolic stability. It is primarily sought by research and development teams in the pharmaceutical, biotechnology, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where its spirocyclic core can enhance target binding and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Investigated as a monomer or additive for producing high-performance polymers with specific thermal or mechanical properties.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	7-Oxa-1-Azaspiro[4.4]Nonane-2,6-Dione,(5R)-(9Ci)
CAS No.	219503-87-4
Molecular Formula	C7H9NO3
Molecular Weight	155.15 g/mol
Synonyms	(5R)-7-Oxa-1-azaspiro[4.4]nonane-2,6-dione; (R)-7-Oxa-1-azaspiro[4.4]nonane-2,6-dione; (5R)-1-Aza-7-oxaspiro[4.4]nonane-2,6-dione; (R)-1-Aza-7-oxaspiro[4.4]nonane-2,6-dione; (R)-Spiroglutarimide; (5R)-Spiroglutarimide; (R)-2,6-Dioxo-7-oxa-1-azaspiro[4.4]nonane
EINECS	Contact for details

Quality Control

Our 7-Oxa-1-Azaspiro[4.4]Nonane-2,6-Dione,(5R)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for research and process development. A detailed Certificate of Analysis (COA) providing purity, enantiomeric excess, and impurity profiles is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.