Description

Carbamic Acid, [[(4R)-5-Oxo-1,3-Dioxolan-4-Yl]Methyl]-, 1,1-Dimethylethyl Ester is a high-purity, chiral chemical intermediate of significant importance in advanced organic synthesis. Its core value lies in its role as a key building block for constructing complex, biologically active molecules, particularly in the pharmaceutical sector. This compound is essential for research and development chemists and process scale-up teams working on novel therapeutics, including protease inhibitors and other specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the synthesis of complex drug candidates, particularly those targeting viral proteases.
• Peptidomimetic Research: Used to introduce protected amino acid-like structures into peptide backbones for drug discovery.
• Asymmetric Synthesis: Serves as a valuable starting material or intermediate in catalytic asymmetric reactions due to its defined stereochemistry.
• API Development: Employed in the research, development, and pilot-scale production of new Active Pharmaceutical Ingredients (APIs).
• Custom Synthesis: A key substrate for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.
• Academic Research: Utilized in university and institutional labs for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	Carbamic Acid, [[(4R)-5-Oxo-1,3-Dioxolan-4-Yl]Methyl]-, 1,1-Dimethylethyl Ester
CAS No.	219325-41-4
Molecular Formula	C10H15NO5
Molecular Weight	229.23 g/mol
Synonyms	tert-Butyl N-[[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]carbonyl]carbamate; (4R)-4-[[(tert-Butoxycarbonyl)amino]methyl]-1,3-dioxolan-2-one; Boc-D-4-Oxazolidinecarboxylic Acid; (R)-4-((tert-Butoxycarbonylamino)methyl)-1,3-dioxolan-2-one; (R)-4-(Boc-aminomethyl)-1,3-dioxolan-2-one; (4R)-4-[(Boc-amino)methyl]-1,3-dioxolan-2-one; Boc-Amino Acid Dioxolanone Derivative
EINECS	Contact for details

Quality Control

Every batch of our Carbamic Acid, [[(4R)-5-Oxo-1,3-Dioxolan-4-Yl]Methyl]-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and chiral integrity meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.