Description

Ethyl (2Z,5S,6E)-5-{[tert-Butyl(Dimethyl)Silyl]Oxy}-2,6-Dimethyl-7-(2-Methyl-1,3-Thiazol-4-Yl)Hepta-2,6-Dienoate is a sophisticated, high-purity synthetic intermediate featuring a protected hydroxyl group and a thiazole heterocycle. This compound is of critical importance in advanced pharmaceutical research and development, particularly in the synthesis of complex bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting infectious diseases or cancer.
• Process Chemistry: Used in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies by providing a versatile scaffold for molecular diversification.
• Agrochemical Synthesis: Intermediate in the development of new pesticides or herbicides with specific biological activity.
• Chemical Biology Probes: Serves as a precursor for labeled compounds or probes used to study biological pathways.
• Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis.

Basic Information

Item	Detail
Product Name	Ethyl (2Z,5S,6E)-5-{[tert-Butyl(Dimethyl)Silyl]Oxy}-2,6-Dimethyl-7-(2-Methyl-1,3-Thiazol-4-Yl)Hepta-2,6-Dienoate
CAS No.	218614-04-1
Molecular Formula	C23H39NO3SSi
Molecular Weight	437.71 g/mol
Synonyms	Ethyl 5-[(tert-Butyldimethylsilyl)oxy]-2,6-dimethyl-7-(2-methyl-4-thiazolyl)-2,6-heptadienoate; (2Z,5S,6E)-Ethyl 5-[(tert-butyldimethylsilyl)oxy]-2,6-dimethyl-7-(2-methyl-1,3-thiazol-4-yl)hepta-2,6-dienoate; TBS-protected thiazole heptadienoate ester; CAS 218614-04-1; Ethyl 5-(TBDMSO)-2,6-dimethyl-7-(2-methylthiazol-4-yl)hepta-2,6-dienoate
EINECS	Contact for details

Quality Control

Our Ethyl (2Z,5S,6E)-5-{[tert-Butyl(Dimethyl)Silyl]Oxy}-2,6-Dimethyl-7-(2-Methyl-1,3-Thiazol-4-Yl)Hepta-2,6-Dienoate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity suitable for research and development. Certificates of Analysis (COA) with full characterization data are available upon request. We adhere to cGMP guidelines where applicable to support our clients' regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container to prevent degradation. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous oil or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.