Description

3-(2-Oxo-Ethyl)-Morpholine-4-Carboxylic Acid tert-Butyl Ester is a high-purity, protected morpholine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug candidates, particularly those containing morpholine or piperazine scaffolds.
• Peptidomimetic Research: Used in the design and synthesis of peptidomimetics and protease inhibitors due to its amide-like structure and protective group.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and insecticides with enhanced activity.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP guidelines.
• Academic and Discovery Chemistry: Utilized in university and institutional labs for methodological development and exploring new chemical spaces.

Basic Information

Product Name	3-(2-Oxo-Ethyl)-Morpholine-4-Carboxylic Acid tert-Butyl Ester
CAS No.	218594-01-5
Molecular Formula	C11H19NO4
Molecular Weight	229.27 g/mol
Synonyms	tert-Butyl 3-(2-oxoethyl)morpholine-4-carboxylate; 4-(tert-Butoxycarbonyl)-3-(2-oxoethyl)morpholine; 3-(2-Oxoethyl)morpholine-4-carboxylic acid 1,1-dimethylethyl ester; Boc-3-(2-oxoethyl)morpholine; N-Boc-3-(2-oxoethyl)morpholine; Morpholine-4-carboxylic acid, 3-(2-oxoethyl)-, 1,1-dimethylethyl ester; 218594-01-5
EINECS	Contact for details

Quality Control

Every batch of 3-(2-Oxo-Ethyl)-Morpholine-4-Carboxylic Acid tert-Butyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.