Description

4-Ethyl 1-Methyl 2-Nitroterephthalate is a specialized nitro-substituted terephthalate ester, a key intermediate in advanced organic synthesis. Its value lies in its precise molecular architecture, which enables the controlled introduction of functional groups for creating complex molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for synthesizing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of potential drug candidates, especially those requiring nitro-aromatic precursors.
• Agrochemical Synthesis: Used in the research and development of new herbicides, pesticides, and plant growth regulators where the nitro and ester functionalities are key.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a precursor in the development of electron-transport or emissive layer materials for electronic displays.
• Polymer Modification: Employed to introduce nitro-aromatic groups into polymer chains, altering properties like solubility, thermal stability, or optical characteristics.
• Dye and Pigment Intermediate: Functions in the synthesis of complex nitro-aromatic dyes and high-performance pigments.
• Cross-Coupling Reactions: Utilized as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create biaryl structures.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry and for exploring new synthetic pathways.

Basic Information

Product Name	4-Ethyl 1-Methyl 2-Nitroterephthalate
CAS No.	218590-76-2
Molecular Formula	C12H13NO6
Molecular Weight	267.24 g/mol
Synonyms	1,4-Benzenedicarboxylic acid, 2-nitro-, 1-ethyl 4-methyl ester; Methyl 4-ethyl 2-nitroterephthalate; 2-Nitroterephthalic acid 1-ethyl 4-methyl ester; 4-Ethyl 1-methyl 2-nitrobenzene-1,4-dicarboxylate; 2-Nitro-1,4-benzenedicarboxylic acid ethyl methyl ester; Ethyl methyl 2-nitroterephthalate; 1-Ethyl 4-methyl 2-nitroterephthalate
EINECS	Contact for details

Quality Control

Our 4-Ethyl 1-Methyl 2-Nitroterephthalate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with lot-specific data are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to store the material under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.