Description

Methyl 3-Amino-5-Iodobenzoate is a high-purity iodinated aromatic ester building block, essential for advanced organic synthesis and pharmaceutical research. This compound serves as a critical intermediate for constructing complex molecules, offering a reactive amino group and a versatile iodine handle for cross-coupling reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug discovery.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a precursor for advanced polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for Suzuki, Sonogashira, and other palladium-catalyzed coupling reactions to create biaryl structures.
• Chemical Biology: Utilized as a probe or linker in bioconjugation and labeling applications due to its reactive functional groups.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	Methyl 3-Amino-5-Iodobenzoate
CAS No.	217314-45-9
Molecular Formula	C8H8INO2
Molecular Weight	277.06 g/mol
Synonyms	3-Amino-5-iodobenzoic acid methyl ester; Methyl 3-amino-5-iodobenzoate; Benzoic acid, 3-amino-5-iodo-, methyl ester; 5-Iodo-3-aminobenzoic acid methyl ester; Methyl 5-iodo-3-aminobenzoate; 217314-45-9; Methyl m-amino-p-iodobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-5-Iodobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.