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8-Azido-Octanoic Acid CAS NO 217180-76-2
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CAS No.:217180-76-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
8-Azido-Octanoic Acid is a versatile bifunctional organic compound featuring a carboxylic acid group and a reactive azide moiety. This unique structure makes it a valuable click chemistry reagent and a critical building block for synthesizing complex molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, bioconjugation, and materials science industries for applications such as drug discovery and polymer modification.
Application
- Click Chemistry Reagent: Used in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and labeling.
- Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs) and prodrugs.
- Bioconjugation Linker: Facilitates the covalent attachment of molecules (e.g., drugs, dyes, polymers) to biomolecules like proteins, peptides, and antibodies.
- Polymer Functionalization: Used to introduce azide groups into polymer chains for subsequent modification or cross-linking to create advanced materials.
- Proteomics Research: Employed in chemical proteomics for activity-based protein profiling (ABPP) and identifying enzyme targets.
- Surface Modification: Applied to functionalize surfaces (e.g., nanoparticles, chips, beads) with azide groups for immobilization studies.
- Lipid Probe Synthesis: A precursor for creating azide-tagged lipid analogs used in metabolic labeling and imaging studies.
Basic Information
| Product Name | 8-Azido-Octanoic Acid |
| CAS No. | 217180-76-2 |
| Molecular Formula | C8H15N3O2 |
| Molecular Weight | 185.22 g/mol |
| Synonyms | 8-Azidooctanoic Acid; Octanoic acid, 8-azido-; 8-Azidocaprylic Acid; Azido-PEG7-acid; ω-Azidooctanoic Acid; N3-C7-COOH; 8-Azido-1-octanoic Acid; Azido-PEG6-carboxylic Acid |
| EINECS | Contact for details |
Quality Control
Our 8-Azido-Octanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to the light-sensitive nature of the azide functional group, prolonged exposure to light should be avoided. Keep away from heat, sparks, open flames, and strong oxidizing agents.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid or low-melting solid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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