Description

6-Rox, Se CAS NO 216699-36-4 is a specialized selenium-containing fluorescent dye derivative, primarily utilized as a critical reagent in advanced molecular biology and diagnostic applications. Its core value lies in its ability to provide highly sensitive and specific detection capabilities, which are essential for modern analytical techniques. This product is particularly vital for research institutions, pharmaceutical developers, and diagnostic kit manufacturers engaged in nucleic acid analysis, hybridization assays, and high-throughput screening.

Application

• Real-Time PCR (qPCR) Probes: Used as a key component in the synthesis of fluorescently labeled probes for quantitative gene expression analysis and pathogen detection.
• In Situ Hybridization (ISH): Serves as a labeling agent for the detection and localization of specific nucleic acid sequences within cells or tissue sections.
• Next-Generation Sequencing (NGS): Employed in the preparation of sequencing libraries and as a fluorescent marker in certain sequencing-by-synthesis platforms.
• Microarray Technology: Acts as a fluorescent tag for labeling cDNA or cRNA targets to be hybridized onto DNA microarrays for genomic and transcriptomic studies.
• Fluorescence Resonance Energy Transfer (FRET) Assays: Functions as a donor or acceptor dye in FRET-based assays for studying molecular interactions and enzymatic activity.
• Diagnostic Kit Manufacturing: A critical raw material for the production of in vitro diagnostic (IVD) reagents and kits for clinical testing.

Basic Information

Product Name	6-Rox, Se
CAS No.	216699-36-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	6-Carboxy-X-rhodamine, SE; 6-ROX, succinimidyl ester; 6-Carboxy-X-rhodamine N-succinimidyl ester; X-rhodamine-6-carboxylic acid, succinimidyl ester; 6-ROX NHS ester; 6-ROX, SE; 6-Carboxy-X-rhodamine, N-hydroxysuccinimide ester; Rhodamine derivative 6-ROX, SE
EINECS	Contact for details

Quality Control

Our 6-Rox, Se is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive life science applications. A comprehensive Certificate of Analysis (COA) detailing purity, absorbance/fluorescence properties, and moisture content is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	Red to dark red powder or solid
Identification (HPLC/UV-Vis)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Absorbance (λmax)	Contact for details
Emission (λmax)	Contact for details
Extinction Coefficient (ε)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.