Description

4-(tert-Butyldimethylsilyl)Oxy-2-Nitroaniline is a specialized aromatic amine derivative featuring a tert-butyldimethylsilyl (TBDMS) protecting group. This compound is a critical high-purity intermediate in advanced organic synthesis, particularly valued for its role in constructing complex pharmaceutical and agrochemical molecules. It is primarily required by R&D laboratories and fine chemical manufacturers engaged in the development of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring protected phenolic or aniline functionalities.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or emissive layer materials in display technology.
• Dye and Pigment Manufacturing: Intermediate for creating specialized azo dyes and high-performance pigments.
• Academic and Industrial Research: Employed in methodological studies and the development of new synthetic pathways in organic chemistry.
• Material Science: Used in the synthesis of monomers or additives for advanced polymers and functional materials.

Basic Information

Product Name	4-(tert-Butyldimethylsilyl)Oxy-2-Nitroaniline
CAS No.	215656-99-8
Molecular Formula	C12H20N2O3Si
Molecular Weight	268.39 g/mol
Synonyms	2-Nitro-4-[(tert-butyldimethylsilyl)oxy]aniline; 4-(TBDMS-Oxy)-2-Nitroaniline; 4-[(tert-Butyldimethylsilyl)oxy]-2-nitrobenzenamine; 2-Nitro-4-(tert-butyldimethylsiloxy)aniline; Benzenamine, 4-[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-nitro-; 4-(tert-Butyldimethylsilanyloxy)-2-nitro-phenylamine; 4-(TBDMSO)-2-Nitroaniline; 4-(tert-Butyldimethylsilyloxy)-2-nitroaniline
EINECS	Contact for details

Quality Control

Every batch of 4-(tert-Butyldimethylsilyl)Oxy-2-Nitroaniline is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are suitable for use in GMP-compliant synthesis upon request. A detailed Certificate of Analysis (COA) with batch-specific data from HPLC, NMR, and GC-MS is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.