Description

3-(n-Butoxycarbonylamino)Propylisocyanide is a specialized organic building block featuring both a protected amine and a reactive isocyanide functional group. This unique bifunctional structure makes it a valuable intermediate for the synthesis of complex molecules, particularly in medicinal chemistry and peptide mimetics. It is primarily utilized by research institutions and pharmaceutical companies for the development of novel drug candidates and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of peptidomimetics and heterocyclic compounds for drug discovery programs.
• Ugi Reaction Component: Serves as the isocyanide component in multi-component Ugi reactions to efficiently generate diverse chemical libraries.
• Peptide Backbone Modification: Used to introduce structural diversity and stability into peptide chains by incorporating isocyanide-derived moieties.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and material science applications.
• Chemical Biology Probes: Facilitates the creation of activity-based probes and molecular tags for studying biological systems.

Basic Information

Product Name	3-(n-Butoxycarbonylamino)Propylisocyanide
CAS No.	215254-92-5
Molecular Formula	C9H16N2O2
Molecular Weight	184.24 g/mol
Synonyms	Boc-aminopropyl isocyanide; 3-[(tert-Butoxycarbonyl)amino]propyl isocyanide; 1-Isocyano-3-[(tert-butoxycarbonyl)amino]propane; N-Boc-3-aminopropyl isocyanide; tert-Butyl N-(3-isocyanopropyl)carbamate; 3-(Boc-amino)propyl isocyanide; (3-Isocyanopropyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 3-(n-Butoxycarbonylamino)Propylisocyanide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C. Due to its highly volatile nature, allow the container to reach room temperature before opening to minimize loss and ensure safe handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.