Description

1-Azido-2-(2-(2-Ethoxyethoxy)Ethoxy)Ethane >=95% is a specialized azide-functionalized polyethylene glycol (PEG) derivative, also known as an azido-PEG3-ethyl ether. This compound matters as a versatile heterobifunctional linker for click chemistry, enabling efficient and selective conjugation of biomolecules, polymers, and materials under mild, aqueous conditions. It is essential for researchers and manufacturers in pharmaceuticals, bioconjugation, and materials science who require reliable, high-purity building blocks for developing targeted drug delivery systems, diagnostic probes, and advanced functional polymers.

Application

• Bioconjugation and Click Chemistry: Serves as a key linker for copper-catalyzed azide-alkyne cycloaddition (CuAAC) to attach drugs, peptides, or fluorescent labels to antibodies, proteins, or nanoparticles.
• Pharmaceutical Development: Used in the synthesis of antibody-drug conjugates (ADCs) and prodrugs, where its hydrophilic PEG spacer improves solubility and pharmacokinetics.
• Polymer and Materials Science: Acts as a functional monomer or crosslinker for creating hydrogels, smart materials, and surface coatings with tailored properties.
• Diagnostic Reagents: Facilitates the labeling of oligonucleotides, proteins, or cells for imaging and diagnostic assay development.
• Chemical Biology Probes: Enables the study of biomolecular interactions and cellular processes through site-specific labeling strategies.
• Ligand and Catalyst Immobilization: Used to tether catalysts or ligands onto solid supports for applications in catalysis and separation sciences.

Basic Information

Product Name	1-Azido-2-(2-(2-Ethoxyethoxy)Ethoxy)Ethane >=95%
CAS No.	215181-72-9
Molecular Formula	C10H21N3O3
Molecular Weight	231.29 g/mol
Synonyms	Azido-PEG3-ethyl ether; 2-[2-(2-Azidoethoxy)ethoxy]ethoxyethane; 11-Aza-3,6,9-trioxa-1-dodecanyl azide; 1-Azido-2,5,8,11-tetraoxadodecane; 3,6,9-Trioxa-11-azadodecyl azide; Azido-tri(ethylene glycol) ethyl ether; N3-PEG3-OEt; Azido-PEG3-O-ethyl
EINECS	Contact for details

Quality Control

Our 1-Azido-2-(2-(2-Ethoxyethoxy)Ethoxy)Ethane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided to guarantee the product meets the declared ≥95% purity and is suitable for sensitive applications like bioconjugation and pharmaceutical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the container to reach room temperature before opening to minimize moisture ingress. Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.