Description

m-Peg2-Azide is a specialized bifunctional polyethylene glycol (PEG) linker featuring an azide group, widely used in bioconjugation and click chemistry applications. This compound is essential for creating stable, site-specific linkages between biomolecules and other functional materials under mild, aqueous conditions. It is a critical reagent for researchers and manufacturers in the pharmaceutical, biotechnology, and materials science industries developing advanced drug delivery systems, diagnostic probes, and functionalized surfaces.

Application

• Bioconjugation and Antibody-Drug Conjugate (ADC) Development: Used as a hydrophilic spacer to conjugate cytotoxic drugs to monoclonal antibodies, improving solubility and pharmacokinetics.
• Click Chemistry Reactions: The azide group readily participates in copper-catalyzed azide-alkyne cycloaddition (CuAAC) with alkynes for efficient, high-yield ligation.
• Polymer and Surface Functionalization: Enables the modification of polymers, nanoparticles, and solid supports with bioactive molecules for targeted applications.
• Peptide and Protein Labeling: Facilitates the site-specific attachment of fluorophores, affinity tags, or other probes to peptides and proteins.
• Prodrug Synthesis: Employed in the design of prodrugs where the active pharmaceutical ingredient is released upon specific biological triggers.
• Hydrogel and Biomaterial Fabrication: Serves as a crosslinking agent in the creation of biocompatible hydrogels for tissue engineering and controlled release.

Basic Information

Product Name	m-Peg2-Azide
CAS No.	215181-61-6
Molecular Formula	C9H17N3O4
Molecular Weight	231.25 g/mol
Synonyms	2-[2-(2-Azidoethoxy)ethoxy]ethanol; Azido-PEG2-alcohol; 2,2'-Ethylenedioxybis(ethyl azide); m-PEG2-N3; Azidoethoxyethoxyethanol; 11-Aza-3,6,9-trioxa-1-dodecanol; 1-Azido-3,6-dioxa-8-octanol; 2-(2-(2-Azidoethoxy)ethoxy)ethan-1-ol
EINECS	Contact for details

Quality Control

Our m-Peg2-Azide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FT-IR, to ensure high purity and consistent performance for sensitive bioconjugation workflows. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under inert atmosphere for long-term stability. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.