Description

(R)-Flumequine CAS NO 215178-95-3 is the enantiomerically pure (R)-isomer of the synthetic antibacterial agent flumequine. This high-purity chiral intermediate is critical for pharmaceutical research and development, particularly in the synthesis of novel, targeted antimicrobial agents. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for applications requiring stereochemical specificity.

Application

• Chiral Intermediate in API Synthesis: Serves as a key building block for the research and development of new antibacterial active pharmaceutical ingredients (APIs).
• Pharmacological Research: Used in studies to investigate the structure-activity relationship (SAR) and efficacy of stereoisomers of quinolone antibiotics.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in chiral separation techniques like HPLC.
• Process Chemistry Development: Essential for developing and optimizing enantioselective synthetic routes in pharmaceutical manufacturing.
• Asymmetric Catalysis Studies: Utilized as a substrate or ligand precursor in research focused on novel catalytic asymmetric transformations.

Basic Information

Product Name	(R)-Flumequine
CAS No.	215178-95-3
Molecular Formula	C14H12FNO3
Molecular Weight	261.25 g/mol
Synonyms	(R)-9-Fluoro-6,7-dihydro-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic Acid; (R)-Flumequine; (R)-9-Fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic Acid; (R)-9-Fluoro-6,7-dihydro-5-methyl-1-oxo-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic Acid; (R)-Flumeguin; (R)-Flumekin; (R)-Flumequine Enantiomer
EINECS	Contact for details

Quality Control

Our (R)-Flumequine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) providing identity, purity, and chiral excess data is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (R)-enantiomer
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.