Description

2,3-Dihydro-1-Benzofuran-5-Yl Isocyanate is a specialized aromatic isocyanate building block used in advanced organic synthesis. This compound is valued for its reactivity as an isocyanate group donor, enabling the formation of ureas and carbamates under mild conditions. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for producing specialty polyurethanes, coatings, and adhesives with specific thermal or mechanical properties.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation, labeling biomolecules, or creating activity-based probes.
• Liquid Crystal & OLED Material Development: Incorporated into the synthesis of advanced organic electronic materials due to the benzofuran core's electronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied for custom research projects and scale-up processes requiring high-purity, specialized isocyanates.

Basic Information

Product Name	2,3-Dihydro-1-Benzofuran-5-Yl Isocyanate
CAS No.	215162-92-8
Molecular Formula	C9H7NO2
Molecular Weight	161.16 g/mol
Synonyms	5-Isocyanato-2,3-dihydrobenzofuran; 2,3-Dihydrobenzofuran-5-yl isocyanate; 5-Isocyanato-2,3-dihydro-1-benzofuran; Benzofuran-5-yl isocyanate, 2,3-dihydro-; 215162-92-8; 2,3-Dihydro-1-benzofuran-5-isocyanate
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-1-Benzofuran-5-Yl Isocyanate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive and light-sensitive nature. Keep away from heat, open flames, and sources of ignition. Isocyanate compounds should be stored separately from amines, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.