Description

1H-Pyrazole-3-Carbonitrile, 4,5-Dihydro-4-(1-Hydroxyethylidene)-1-Methyl-5- is a high-value, functionalized pyrazole derivative serving as a critical advanced pharmaceutical intermediate and organic synthesis building block. Its unique molecular scaffold, featuring both nitrile and hydroxyethylidene functional groups, makes it indispensable for constructing complex heterocyclic compounds. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used to create specialized pyrazole-based ligands for transition metal catalysis and coordination chemistry.
• Material Science Research: Intermediate in the development of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Serves as a core structure for designing enzyme inhibitors or molecular probes for biological pathway analysis.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific heterocyclic framework.

Basic Information

Product Name	1H-Pyrazole-3-Carbonitrile, 4,5-Dihydro-4-(1-Hydroxyethylidene)-1-Methyl-5-
CAS No.	214893-58-0
Molecular Formula	C7H9N3O
Molecular Weight	151.17 g/mol
Synonyms	4-(1-Hydroxyethylidene)-1-methyl-4,5-dihydro-1H-pyrazole-3-carbonitrile; 1-Methyl-4-(1-hydroxyethylidene)-4,5-dihydro-1H-pyrazole-3-carbonitrile; 4,5-Dihydro-4-(1-hydroxyethylidene)-1-methyl-1H-pyrazole-3-carbonitrile; 3-Cyano-4-(1-hydroxyethylidene)-1-methyl-4,5-dihydro-1H-pyrazole; Pyrazole-3-carbonitrile derivative (CAS 214893-58-0)
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrazole-3-Carbonitrile, 4,5-Dihydro-4-(1-Hydroxyethylidene)-1-Methyl-5- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical parameters. Our quality system is designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be light-sensitive and/or hygroscopic; therefore, containers should be kept sealed under an inert atmosphere when not in use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.