Description

2-Acetamido-3,4,6-Tri-o-Benzyl-2-Deoxy-β-D-Glucopyranosyl Azide is a sophisticated, protected glycosyl donor building block, specifically designed for the synthesis of complex oligosaccharides and glycoconjugates. Its value lies in providing a reactive azide group and protected hydroxyls, enabling precise and efficient glycosylation reactions under controlled conditions. This compound is essential for researchers and process chemists in pharmaceutical development, particularly for creating novel carbohydrate-based drugs, vaccines, and diagnostic agents.

Application

• Glycochemistry Research: A key intermediate for the solid-phase and solution-phase synthesis of complex oligosaccharides and glycans.
• Pharmaceutical Development: Building block for the creation of glycosylated active pharmaceutical ingredients (APIs), prodrugs, and carbohydrate-based therapeutics.
• Vaccine Adjuvant Synthesis: Used in the preparation of synthetic carbohydrate antigens and immunostimulatory compounds for conjugate vaccine development.
• Glycopeptide & Glycoprotein Mimetics: Enables the site-specific introduction of carbohydrate motifs onto peptide backbones for biological studies.
• Chemical Biology Probes: Serves as a precursor for "click chemistry" applications via azide-alkyne cycloaddition to label or functionalize biomolecules.
• Process Chemistry: Scalable intermediate for the GMP production of carbohydrate-derived drug candidates.

Basic Information

Item	Detail
Product Name	2-Acetamido-3,4,6-Tri-o-Benzyl-2-Deoxy-β-D-Glucopyranosyl Azide
CAS No.	214467-60-4
Molecular Formula	C29H30N4O5
Molecular Weight	514.58 g/mol
Synonyms	2-Acetamido-3,4,6-tri-O-benzyl-2-deoxy-β-D-glucopyranosyl azide; 2-Acetamido-2-deoxy-3,4,6-tri-O-benzyl-β-D-glucopyranosyl azide; 1-Azido-2-acetamido-3,4,6-tri-O-benzyl-2-deoxy-β-D-glucopyranose; β-D-Glucopyranosyl azide, 2-(acetylamino)-2-deoxy-3,4,6-tris-O-(phenylmethyl)-; GlcNAc(β)-N3 (Benzyl Protected); Benzyl-protected N-Acetylglucosamine Azide
EINECS	Contact for details

Quality Control

Our production of 2-Acetamido-3,4,6-Tri-o-Benzyl-2-Deoxy-β-D-Glucopyranosyl Azide adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is fully characterized by NMR, HPLC, and MS to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to maintain stability. Keep container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.